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FLASH GENE
Symbol TMC2 contributors: mct - updated : 12-12-2017
HGNC name transmembrane channel-like 2
HGNC id 16527
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Tmc2
ortholog to zebrafish Tmc2a
intraspecies homolog to TMC1
Homologene
FAMILY
  • TMC family
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • may be crucial for normal auditory function
  • LHFPL5, TMIE, TMC1, and TMC2 have so far been linked to the transduction channel
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • PCDH15 interacts with transmembrane channel-like proteins TMC1 and TMC2
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS