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FLASH GENE

Symbol

MT-ND6

contributors: shn - updated : 13-11-2012

HGNC name	mitochondrially encoded NADH dehydrogenase 6
HGNC id	7462

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

Mice with mtDNA ND6 P25L mutation display reduction in retinal function by elecroretinogram, age-related decline in central smaller caliber optic nerve fibers with sparing of larger peripheral fibers, neuronal accumulation of abnormal mitochondria, axonal swelling, and demyelination mostly due to oxidative stress