Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

BDKRB1

contributors: mct - updated : 16-04-2020

HGNC name	bradykinin receptor B1
HGNC id	1029

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in subcutaneous white adipose tissue (sWAT) in patients with coronary artery disease (CAD)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	serum BDKRB1 levels may provide prognostic information and currently act as potential indicators for progression in atherosclerosis
Therapy target
	System Type Disorder Pubmed immunology inflammatory   its inhibition can reduce BBB damage and cell invasion during autoimmune CNS disease and may offer a novel anti-inflammatory strategy for the treatment of MS miscelleaneous urinary   blockade of the BDKRB1 has significant potential for the treatment of glomerulonephritis

ANIMAL & CELL MODELS

Bdkrb1 is upregulated by the oxidative stress in the brain of insulin-resistant rats and its activation causes stereotypic nocifensive behavior through the release of substance P, glutamate and NO