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FLASH GENE
Symbol PRKD2 contributors: mct - updated : 02-06-2015
HGNC name protein kinase D2
HGNC id 17293
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
leads to increased proliferation and invasion of BON endocrine cells
tumoral     --over  
in pancreatic cancer
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerhemopathy 
pharmacologic inhibition of PRKD2 may represent a valuable approach to targeting the leukemic stem cell (LSC) in CML
cancerbrainglioma/neuroblstoma
PRKD2-GOLPH3-AKT signaling pathway might be a potential glioma therapeutic target
ANIMAL & CELL MODELS