Symbol
| PRKD2
| contributors: mct - updated : 02-06-2015
|
HGNC name
| protein kinase D2
|
HGNC id
| 17293
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
leads to increased proliferation and invasion of BON endocrine cells | tumoral
|  
|  
| --over
|  
|
in pancreatic cancer | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cancer | hemopathy | | |
pharmacologic inhibition of PRKD2 may represent a valuable approach to targeting the leukemic stem cell (LSC) in CML | cancer | brain | glioma/neuroblstoma | |
PRKD2-GOLPH3-AKT signaling pathway might be a potential glioma therapeutic target |
| | | |