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FLASH GENE
Symbol CAP2 contributors: mct - updated : 03-05-2017
HGNC name CAP, adenylate cyclase-associated protein, 2 (yeast)
HGNC id 20039
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • C-terminal fragment of CAP2 interacts with actin, indicating that CAP2 has the capacity to bind to actin
  • HOMOLOGY
    interspecies homolog to murine Cap2
    ortholog to rattus Cap2
    ortholog to murine 2810452G09Rik
    homolog to Drosophila capt
    homolog to C.elegans F41G4.2a
    intraspecies homolog to CAP1
    Homologene
    FAMILY
  • CAP family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus
    text
  • found in the nucleus in undifferentiated myoblasts and at the M-line of differentiated myotubes
  • enriched in the nucleus, and sparse in the cytosol
  • basic FUNCTION
  • involved in establishment and/or maintenance of cell polarity
  • having a regulatory bifunctional role
  • C-terminal fragment of CAP2 interacts with actin, indicating that CAP2 has the capacity to bind to actin
  • has the capacity to bind to actin
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    text cell polarity
    PATHWAY
    metabolism
    signaling signal transduction
    cAMP pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to adenyl cyclase binding, CAP, actin
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS