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FLASH GENE

Symbol

C21orf91

contributors: mct - updated : 03-05-2021

HGNC name	chromosome 21 open reading frame 91
HGNC id	16459

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   elevated C21orf91 expression levels induce a gliogenic shift towards the astrocytic lineage reflecting non-equilibrated glial cell populations in Down syndrome brains

Susceptibility

to cold sore

Variant & Polymorphism	different alleles of the newly described gene C21orf91 affect the expression of cold sore phenotypes

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS