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FLASH GENE
Symbol AP2A2 contributors: npt/ - updated : 30-03-2006
HGNC name adaptor-related protein complex 2, alpha 2 subunit
HGNC id 562
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Ap2a2 adaptor protein complex AP-2 alpha 2 subunit
Homologene
FAMILY
  • adaptor complexes large subunit family
    • CATEGORY adaptor , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    text endocytic coated vesicles
    basic FUNCTION
  • AP2 adaptor complex linking clathrin to receptors in coated vesicles, clathrin-associated protein complexes are believed to interact with cytoplasmic domains of transmembrane proteins leading to their selection and concentration
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
  • component of AP-2 adaptor complex, clathrin coat assembly complex
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • HIP1
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS