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FLASH GENE
Symbol AP2A2 contributors: npt/ - updated : 30-03-2006
HGNC name adaptor-related protein complex 2, alpha 2 subunit
HGNC id 562
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
Nervousbrain   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Ap2a2 adaptor protein complex AP-2 alpha 2 subunit
Homologene
FAMILY
  • adaptor complexes large subunit family
    • CATEGORY adaptor , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    text endocytic coated vesicles
    basic FUNCTION
  • AP2 adaptor complex linking clathrin to receptors in coated vesicles, clathrin-associated protein complexes are believed to interact with cytoplasmic domains of transmembrane proteins leading to their selection and concentration
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
  • component of AP-2 adaptor complex, clathrin coat assembly complex
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • HIP1
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS