basic FUNCTION
| cadherin related neuronal receptor, putatively involved in the specificty of the neuronal connections |
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may play specific roles in the establishment of selective synaptic connections of specific modality of cerebral cortex with other communicating brain regions such as the thalamus |
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play likely roles in the wiring of neural circuit formation and maintenance through its adhesive and regulatory mechanism |
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PCDH8, PCDH9, PCDH17 and PCDH20 genes are located around 13q21.1 and might be broadly involved in tumor suppression in a variety of tumors |
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is a functional tumor suppressor and an important antagonist of WNT/CTNNB1 signaling and epithelial-mesenchymal transition (EMT), with frequent epigenetic inactivation in Nasopharyngeal Carcinoma |
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likely specific role in the sensory epithelium of the utricle and cochlea |
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involved in the disruption of hypopharyngeal squamous cell carcinoma (HSCC) progression through antagonizing its downstream WNT/CTNNB1 signalling pathway |
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may be involved in taste quality-specific connections between differentiated taste cells and their partner neurons, thereby acting as a molecular tag for the coding of sweet and/or umami taste |