Symbol
| TRIM31
| contributors: mct/npt - updated : 02-04-2020
|
HGNC name
| tripartite motif-containing 31
|
HGNC id
| 16289
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
in gastric adenocarcinoma | tumoral
|  
|  
|  
| gain of function
|
in Bladder cancer patients when compared with normal subjects | tumoral
|  
|  
| --over
|  
|
in high-grade glioma tissues | tumoral
|  
|  
| --over
|  
|
significantly upregulated in liver cancer tissues compared with paired distal non-cancerous liver tissues from HCC patients | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
| may be a valuable detective marker in primary colorectal cancer (CRC) | |
independent prognostic factor for glioma patients | Therapy target
|
System | Type | Disorder | Pubmed |
cancer | brain | | |
TRIM31 may be an effective target for glioma intervention | cancer | digestive | liver | |
potential therapeutic strategy against HCC by targeting TRIM31 |
| | |
| Trim31-deficient mice were more susceptible to infection with RNA virus than were wild-type mice |