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FLASH GENE

Symbol

TRIM54

contributors: mct/ - updated : 31-03-2007

HGNC name	tripartite motif-containing 54
HGNC id	16008

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional         resulting in accumulation of FHL2 and FLNC, widening of the sarcomere, diminished contractility and susceptibility to ventricular rupture

Susceptibility

to cardiac rupture after myocardial infarction

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS