Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

TRIM63

contributors: mct - updated : 25-10-2013

HGNC name	tripartite motif-containing 63
HGNC id	16007

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

CMH15

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cardiovascular     inhibition of TRIM63 could be a novel mechanism to prevent or reverse muscle wasting associated with various pathologies

ANIMAL & CELL MODELS

	murf1 knock out mice (Bodine 2001)
	the increase in cardiac size in MuRF1 KO mice was related to a decrease in proteasome activity and an increase in Akt signaling relative to WT mice