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FLASH GENE

Symbol

PTRF

contributors: mct/npt - updated : 16-03-2016

HGNC name	polymerase I and transcript release factor
HGNC id	9688

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

CGL4

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in prostate cancer cells contributes significantly to tumour progression and metastasis by promoting the angiogenesis and lymphangiogenesis potential of the cancer cells

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	may be a suitable adipocyte marker for predicting pathological obesity and inform clinical management
Therapy target

ANIMAL & CELL MODELS