basic FUNCTION
| playing a role in the dissociation of paused ternary complexes |
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playing a role in insulin transcriptional control |
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required for caveola formation and sequestration of mobile caveolin into immobile caveolae |
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plays an important role in caveolae formation and organization |
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implicated in regulating caveolae function (Hill 2008) |
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function as caveolin adapter molecules that regulate caveolae function (McMahon 2009) |
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essential for caveolae biogenesis (Rajab 2010) |
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PTRF is a novel regulator of oxidative stress-induced premature senescence by acting as a link between free radicals and activation of the TP53/CDKN1A pathway  |
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quantitatively reduced cell migration, and induced mesenchymal epithelial reversion  |
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PTRF, a structural protein of caveolae, modulates the oncogenic function of CAV1 and cooperates with CAV1 to enhance pancreatic cancer aggressiveness  |
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membrane dynamics in cell migration is affected by caveolae associated PTRF  |
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PTRF is associated with CAV1 at the time of receptivity  |