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FLASH GENE

Symbol

GRIN3A

contributors: mct - updated : 07-10-2015

HGNC name	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
HGNC id	16767

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to schizophrenia to Alzheimer disease (AD)

Variant & Polymorphism other	rare mutations in the GRIN3A gene may contribute to the pathogenesis of schizophrenia in certain patients (Shen 2010)
	G allele was present at a higher rate than the A allele at position 3723 in AD patients compared with normal groups (

Candidate gene	strong candidate for involvement in the etiology of nicotine dependence (Ma 2010)
Marker
Therapy target

ANIMAL & CELL MODELS

Nr3a knockout mice (Das)