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FLASH GENE

Symbol

EIF3J

contributors: - updated : 17-08-2007

HGNC name	eukaryotic translation initiation factor 3, subunit J
HGNC id	3270

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

eukaryotic translation initiation factor family

CATEGORY

RNA associated

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic,ribosome

basic FUNCTION	stabilizing initiator Met tRNA (TRIMs) binding to 40S subunits
	promoting the association of Met tRNA and mRNA

CELLULAR PROCESS

protein, translation/synthesis

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

components of the EIF3 multiprotein complex, 600kDa

INTERACTION

DNA

RNA	binding to 40S ribosomal subunits
	binding to the 18S RNA (required for mRNA binding)

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS