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FLASH GENE
Symbol EIF3J contributors: - updated : 17-08-2007
HGNC name eukaryotic translation initiation factor 3, subunit J
HGNC id 3270
DNA
TYPE functioning gene
STRUCTURE 25.00 kb     9 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine  highly
 salivary gland   highly
Endocrinethyroid   highly
Reproductivefemale systemuteruscervix highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY eukaryotic translation initiation factor family
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic,ribosome
basic FUNCTION
  • stabilizing initiator Met tRNA (TRIMs) binding to 40S subunits
  • promoting the association of Met tRNA and mRNA
    • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component components of the EIF3 multiprotein complex, 600kDa
    INTERACTION
    DNA
    RNA
  • binding to 40S ribosomal subunits
  • binding to the 18S RNA (required for mRNA binding)
    • small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS