Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol EIF3J contributors: - updated : 17-08-2007
HGNC name eukaryotic translation initiation factor 3, subunit J
HGNC id 3270
Location 15q15.3      Physical location : 44.829.265 - 44.854.999
Synonym name
  • eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa
    • Synonym symbol(s) EIF3-P35, EIF3-ALPHA, EIF3S1, eIF3-alpha, eIF3-p35
    DNA
    TYPE functioning gene
    STRUCTURE 25.00 kb     9 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinesmall intestine  highly
     salivary gland   highly
    Endocrinethyroid   highly
    Reproductivefemale systemuteruscervix highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY eukaryotic translation initiation factor family
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION
  • stabilizing initiator Met tRNA (TRIMs) binding to 40S subunits
  • promoting the association of Met tRNA and mRNA
    • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component components of the EIF3 multiprotein complex, 600kDa
    INTERACTION
    DNA
    RNA
  • binding to 40S ribosomal subunits
  • binding to the 18S RNA (required for mRNA binding)
    • small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS