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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

AQP5

contributors: mct - updated : 17-11-2010

HGNC name	aquaporin 5
HGNC id	638

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

PPK1B

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function defective cellular trafficking of AQP5 in the lacrimal glands of Sjogren syndrome tumoral     --over   in lung cancer tissue associated with poor prognosis

Susceptibility

Variant & Polymorphism

Candidate gene	for Sjögren's syndrome (SJGS)
Marker
Therapy target
	System Type Disorder Pubmed neurosensorial     aquaporins appear to be important for the development of novel drug therapies for Meniere's disease and related disorders cancer     attractive therapeutic target in carcinogenesis

ANIMAL & CELL MODELS