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FLASH GENE
Symbol DEFB103A contributors: - updated : 22-11-2005
HGNC name defensin, beta 103A
HGNC id 15967
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains six cysteine motif
HOMOLOGY
interspecies homolog to murine Defb6
homolog to rattus Defb1
Homologene
FAMILY beta-defensin family
CATEGORY immunity/defense
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • antimicrobial activity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text important role in innate epithelial defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by infection of bacteria and TNF alpha
    inhibited by by corticosteroids
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional   amplification    
    higher genomic copy number associated with risk of psoriasis
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS