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FLASH GENE

Symbol

GUCY1A2

contributors: - updated : 21-04-2006

HGNC name	guanylate cyclase 1, soluble, alpha 2
HGNC id	4684

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine adrenal gland       highly   pancreas       highly Lymphoid/Immune spleen       highly Reproductive female system ovary     highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a guanylate cyclase domain

mono polymer

heteromer , dimer

HOMOLOGY

Homologene

FAMILY

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm

basic FUNCTION

having guanylyl cyclase on binding to the beta-1 subunit

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

heterodimerizing with GUCY1B1

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

activated by

by nitric oxide in the presence of magnesium or manganese ions

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS