basic FUNCTION
| SYT3, SYT5, SYT6, and SYT10 exhibit similar Ca2+-dependent phospholipid- and SNARE-binding properties as SYT1, although with a higher apparent Ca2+-affinity |
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functions as the Ca2+-sensor that triggers IGF1 exocytosis in the olfactory bulb neurons |
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controls a previously unrecognized pathway of Ca2+-dependent exocytosis that is spatially and temporally distinct from Ca2+-dependent synaptic vesicle exocytosis controlled by SYT1 |
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acts as a Ca2+-sensor to maintain the normal size and arborization of olfactory bulb neurons, with a function that is unique to this synaptotagmin isoform and not shared by other, closely related synaptotagmins |