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FLASH GENE

Symbol

SYT8

contributors: np/ - updated : 18-06-2008

HGNC name	synaptotagmin VIII
HGNC id	19264

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	11p15.5      Physical location : 1.855.673 - 1.858.750
Synonym name	synaptotagmin 8
Synonym symbol(s)	DKFZp434K0322, SytVIII

DNA

TYPE	functioning gene
STRUCTURE	3.08 kb     9 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_138567 9 - 1423 NP_612634 - 401 - -

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive male system testis

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	an intravesicular N terminal domain
	a single transmembrane (TM) region
	two protein kinase C-homologous repeats (Ca2+ binding domains C2)
	a conserved WHXL motif in the C terminus

mono polymer

homomer , heteromer , complex

HOMOLOGY

interspecies

ortholog to murine Syt8

Homologene

FAMILY

synaptotagmin family

CATEGORY

structural protein

SUBCELLULAR LOCALIZATION

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	metal binding,
	Ca2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS