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FLASH GENE
Symbol COPS3 contributors: npt/ - updated : 19-07-2007
HGNC name COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)
HGNC id 2239
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • PCI (Proteasome,COP9,initiation factor 3) domain
  • INT6 domain
  • NIP1 and TRIP15 domain
    • HOMOLOGY
    interspecies homolog to Arabidopsis subunit 3
    intraspecies homolog to components of the regulatory subunit of 26S proteasome
    homolog to homology to regulatory components of hte 26A proteasome
    Homologene
    FAMILY
  • CSN3 family
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • potential cellular regulator modulating multiple signaling pathways
  • phosphorylating regulators, IKBA, JUN, NFKB1
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
  • component of a signalosome complex GPS1 450kDa including COPS3, COPS4, COPS5/JAB1, COPS6, COPS7A, COPS7B, GPS1, TRIP15
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS