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FLASH GENE

Symbol

BAMBI

contributors: mct - updated : 24-11-2020

HGNC name	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
HGNC id	30251

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   beta-catenin is responsible for the aberrant expression of BAMBI in colorectal tumor cells tumoral     --low   hypermethylation of the BAMBI gene promoter that leads to BAMBI gene suppression may be one of the epigenetic events affecting the invasiveness or aggressiveness of bladder cancers tumoral     --low   n metastatic melanoma cell lines

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS