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FLASH GENE
Symbol SULT1A2 contributors: npt/ - updated : 21-04-2006
HGNC name sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
HGNC id 11454
Location 16p11.2      Physical location : 28.603.265 - 28.608.391
Synonym name
  • aryl sulfotransferase
  • phenol sulfotransferase 2
  • phenolic-metabolizing (P) form of PST
  • thermostable phenol sulfotransferase
  • Synonym symbol(s) HAST2, STIA2, STP2, HAST4, P-PST, MGC142289, TSPST2
    EC.number 2.8.2.1
    DNA
    TYPE functioning gene
    STRUCTURE 5.13 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    text two transcripts encode the same protein
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 1075 - 295 - -
    8 - 1348 - 295 - -
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestivemouthtongue   
    Endocrinethyroid    
    Lymphoid/Immunelymph node    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • the LDQKW sequence motif
  • mono polymer homomer , dimer
    HOMOLOGY
    Homologene
    FAMILY
  • sulfotransferase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • aryl (phenol) sulfotransferase 2, phenol preferring
  • catalyzing the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to breast cancer
    Variant & Polymorphism other SULT1A2*2 allele seems to influence the age of onset among early-onset breast cancer patients
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS