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FLASH GENE
Symbol ZNF177 contributors: npt - updated : 07-05-2009
HGNC name zinc finger protein 177
HGNC id 12966
DNA
TYPE functioning gene
STRUCTURE 19.17 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
motif repetitive sequence   ALU   other
text structure Alu repeats in 5'utr and HERV sequence
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text two alternative forms of exon 9:9a,9b
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 splicing 1839 36 321 - Baban (1996)
- splicing 2320 14 120 - Baban
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N temrinal Krüppel associated box (KRAB) domain
  • 13 zinc finger domains (six imperfect)
    • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to C.elegans F45B8.4
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
    • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • transcriptional regulation
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS