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FLASH GENE

Symbol

MRPL40

contributors: - updated : 16-12-2005

HGNC name	mitochondrial ribosomal protein L40
HGNC id	14491

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular vessel         Digestive mouth tongue         pancreas exocrine

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular

cell lineage
cell lines
fluid/secretion	blood

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies	ortholog to murine Mrpl40
	ortholog to rattus mrpl40

Homologene

FAMILY

CATEGORY

structural protein , RNA associated

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria,matrix
text	mitochondrial ribosome

basic FUNCTION	mitochondrial proteins biosynthesis
	ribosomal structure and biogenesis

CELLULAR PROCESS

protein, translation/synthesis

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

component of the large subunit (39S) of the mitochondrial ribosome, including two RNA molecules and, at least,70 MRPs among which 47 proteins for the large subunit

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS