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FLASH GENE

Symbol

ULBP2

contributors: mct - updated : 22-04-2013

HGNC name	UL16 binding protein 2
HGNC id	14894

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in ovarian cancer highly correlated with that of ULBP2, and high expression of ULBP2 is an indicator of poor prognosis in ovarian cancer and may relate to T cell dysfunction in the tumor microenvironment

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	soluble ULBP2 seems to be useful to identify early-stage patients with risk of B-cell chronic lymphocytic leukemia progression
Therapy target

ANIMAL & CELL MODELS