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FLASH GENE

Symbol

PTDSS1

contributors: KTN/npt - updated : 23/10/2008

HGNC name	phosphatidylserine synthase 1
HGNC id	9587

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed PTDSS1 13 - 2504 55.4 473 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine placenta       moderately Lymphoid/Immune tonsils       moderately Respiratory lung       moderately

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / hematopoietic bone marrow     moderately Connective bone     moderately Muscular       moderately

cell lineage
cell lines
fluid/secretion	moderately in blood, predominantly in lymph

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

putative membrane-spanning domain

HOMOLOGY

interspecies	homolog to dog PTDSS1 (96.2 pc)
	homolog to chimpanzee PTDSS1 (100 pc)
	homolog to cow PTDSS1 (97.7 pc)
	homolog to rattus Ptdss1 (97 pc)
	homolog to murine Ptdss1 (97.3 pc)

Homologene

FAMILY

phosphatidyl serine synthase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria
	intracellular,cytoplasm,organelle,membrane
text	multi-pass membrane protein

basic FUNCTION

catalyzing a base-exchange reaction in which the polar head group of phosphatidylcholine is replaced by L-serine

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

lipid/lipoprotein

signaling

phosphatidylserine biosynthesis

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS