| basic FUNCTION
| required for protein transport from the Golgi apparatus to the endosomes |
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functioning as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface |
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might be involved in developmental or tissue-specific regulation of gene expression |
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with SORCS2 and SORCS3, have diverse, but partly overlapping functions in the developing and mature central nervous system (Hermey 2004) |
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SORL1, SORCS1, SORCS2, and SORCS3) play pleiotropic functions in protein trafficking and intracellular and intercellular signaling in neuronal and non-neuronal cells  |
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regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia |
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sortilin, SORL1, SORCS1, SORCS2, and SORCS3) modulate neurotrophic signaling pathways |
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critical roles in the control of neuronal viability and function |
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SORCS2 plays a role upstream of the intrinsic polarity pathway and there are differences between hair cell types in the deployment of the machinery that generates a precisely organised hair bundle |
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protective role for SORCS2 in neuronal stress response ( |
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is required for social memory |
