Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol KCNK13 contributors: mct/npt - updated : 02-03-2009
HGNC name potassium channel, subfamily K, member 13
HGNC id 6275
Location 14q32.11      Physical location : 90.528.107 - 90.652.195
Synonym name
  • tandem pore domain halothane inhibited K+ channel 1
  • tandem pore domain potassium channel THIK-1
  • Synonym symbol(s) THIK-1, K2p13.1, THIK1
    DNA
    TYPE functioning gene
    STRUCTURE 124.00 kb     2 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 2517 45.4 408 - Theilig (2008)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Urinarykidneytubulecollecting duct   Homo sapiens
     kidneytubuleconvoluted tubuleproximal tubule  Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    intraspecies homolog to KCNK12 (60 p100)
    Homologene
    FAMILY
  • KCNK family
  • two pore domain potassium channel family
  • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • may be involved in both the maintenance of neuronal phenotype and in the specific functional role of these neurons in their respective networks (Jezzini 2004)
  • KCNK12, KCNK13 form active heteromeric channels, further expanding the known repertoire of K(+) channels
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text potassium channel
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS