basic FUNCTION
| may be involved in adhesion events associated with cardiac inflammatory conditions |
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JAM1, JAM2, JAM3 expressions on the lymphatic endothelium may contribute to both seal the cell-cell contact at interendothelial junctions |
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play an important role in the assembly and maintenance of tight junctions and in the establishment of epithelial cell polarity |
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identifies a unique population of RGCs (retinal ganglion cells) in which structure corresponds remarkably to function |
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appears to contribute to leucocyte extravasation by facilitating not only transmigration but also rolling and adhesion |
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is an active player in the maintenance of the bone marrow stromal microenvironment |
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JAMB and JAMC are potentially essential for vertebrate myocyte fusion |
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may play a role in the interaction between hatched blastocyst and receptive uterus |
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role of JAM2, JAM3 in progression of gastric adenocarcinoma |
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may function as a putative tumour suppressor in the progression and metastasis of colorectal cancer |
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is an adhesive ligand interacting with various immune cell types and regulating vascular function and was recently identified as an inhibitor of somatodendritic myelination in spinal cord neurons |