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FLASH GENE
Symbol RAB9B contributors: mct - updated : 29-09-2017
HGNC name RAB9B, member RAS oncogene family
HGNC id 14090
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated LipoP , Other
HOMOLOGY
interspecies homolog to Drosophila EG:52C10.2
homolog to C.elegans F16H9.1b
intraspecies homolog to RAB9
Homologene
FAMILY
  • small GTPase superfamily
  • Rab family
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytosolic,granule
    basic FUNCTION
  • involved in the transport of proteins between the endosomes and the trans Golgi network
  • RAB9A and RAB9B, which are essential for alternative autophagy, but not conventional macroautophagy, severely suppressed mitophagy
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • GTP
    • protein
  • specific and strong interaction of HPS1, HPS4 with the GTP-bound form of the endosomal GTPase, RAB9A, RAB9B
  • RAB9B can bind to SGSM1 probably in a similar manner as RAB9A
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS