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FLASH GENE

Symbol

DOCK1

contributors: mct - updated : 31-12-2018

HGNC name	dedicator of cytokinesis 1
HGNC id	2987

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in acute myeloid leukemia with increased mortality

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

T-lymphoid progenitor cells in fetal mice express two closely related CDM family molecules, Dock2 and Dock1, and the impaired fetal thymus colonization in mice deficient for Dock2 and Dock1 was not as severe as that in mice doubly deficient for Ccr7 and Ccr9