Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ARHGAP9 contributors: mct/npt - updated : 15/09/2008
HGNC name Rho GTPase activating protein 9
HGNC id 14130
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • SRC homology 3 domain
  • RHO GAP domain
  • a pleckstrin homology domain
  • a WW domain
    • HOMOLOGY
    Homologene
    FAMILY
  • Rho GTPase activating family
    • CATEGORY adhesion , regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • regulation of adhesion of hematopoietic cells to extracellular matrix
  • having a function to catalyze the hydrolysis of GTP that is bound to Rho, Rac and/or Cdc42, inactivating these regulators of the actin cytoskeleton
    • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to coronary artery spasm
    Variant & Polymorphism other Ala370Ser polymorphism in the ARHGAP9 gene is associated with coronary artery spasm (Takefuji 2010)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS