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FLASH GENE
Symbol WNT8B contributors: - updated : 11-04-2006
HGNC name wingless-type MMTV integration site family, member 8B
HGNC id 12789
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
cysteine rich with a zinc finger-like motif
conjugated GlycoP
HOMOLOGY
interspecies homolog to Drosophila wingless (Wg) segment polarity gene
Homologene
FAMILY
  • member of the WNT family encoding intercellular signaling molecules
    • CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • modulating cell fate and cell behavior during vertebrate development
  • may be playing key roles in embryonal tumors and embryonic stem cells through synergistic activation of CTNNB-TCF signaling pathway
    • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene candidate gene for partial epilepsy
    Marker
    Therapy target
    ANIMAL & CELL MODELS