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FLASH GENE

Symbol

WNT8B

contributors: - updated : 11-04-2006

HGNC name	wingless-type MMTV integration site family, member 8B
HGNC id	12789

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine adrenal gland         Reproductive female system ovary       Respiratory respiratory tract larynx         respiratory tract trachea

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

fetal, pregnancy

Text	in developing forebrain

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

cysteine rich with a zinc finger-like motif

conjugated

GlycoP

HOMOLOGY

interspecies

homolog to Drosophila wingless (Wg) segment polarity gene

Homologene

FAMILY

member of the WNT family encoding intercellular signaling molecules

CATEGORY

protooncogene

SUBCELLULAR LOCALIZATION

extracellular

basic FUNCTION	modulating cell fate and cell behavior during vertebrate development
	may be playing key roles in embryonal tumors and embryonic stem cells through synergistic activation of CTNNB-TCF signaling pathway

CELLULAR PROCESS

cell communication

PHYSIOLOGICAL PROCESS

development

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene	candidate gene for partial epilepsy
Marker
Therapy target

ANIMAL & CELL MODELS