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FLASH GENE

Symbol

CUL1

contributors: mct/pgu - updated : 20-02-2018

HGNC name	cullin 1
HGNC id	2551

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	dysregulation of cyclin E and early embryonic lethality in CUL1-/-
	cul1-/- sequestrate and inactivate Skp1 leading to genetic instability and neoplastic transformation