Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | AP1S2 | contributors: mct - updated : 06-10-2017 |
HGNC name | adaptor-related protein complex 1, sigma 2 subunit |
HGNC id | 560 |
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Corresponding disease |
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Location | Xp22.2 Physical location : 15.843.929 - 15.873.100 | ||
Synonym name | |||
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Synonym symbol(s) | SIGMA1B, DC22, MGC:1902, MRX59 |
DNA |
TYPE | functioning gene |
STRUCTURE | 29.21 kb 5 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | heteromer , tetramer |
HOMOLOGY |
interspecies | homolog to murine adaptor protein AP1 |
ortholog to S cerevisiae Yap17p |
Homologene |
FAMILY | adaptor complexes small subunits family |
CATEGORY | adaptor , transport carrier |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,Golgi | |
intracellular,cytoplasm,organelle,lysosome | |
intracellular,cytoplasm,cytosolic,vesicle |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | endocytosis transport , cellular trafficking transport |
PATHWAY |
metabolism |
signaling |
a component | |
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INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | MRX59 |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
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