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FLASH GENE
Symbol SPRR2G contributors: - updated : 08-04-2006
HGNC name small proline-rich protein 2G
HGNC id 11267
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a central segment built up from nine octapeptide repeats,*K*PEP*
mono polymer heteromer , tetramer
HOMOLOGY
Homologene
FAMILY potassium channel family, a (shaker) subfamily
CATEGORY transport channel
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton
text cornifin
basic FUNCTION
  • mediating the voltage-dependent potassium ion permeability of excitable membranes
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • clustered in the epidermal differentiation complex (EDC)
  • heterotetramer of potassium channel proteins
    • INTERACTION
    DNA
    RNA
    small molecule
    protein binding PDZ domains of DLG1, DLG2 and DLG4
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS