| Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
| HGNC | UniGene | Nucleotide | OMIM | UCSC |
| Home Page |
| FLASH GENE |
| Symbol | KYNU | contributors: - updated : 17-10-2006 |
| HGNC name | kynureninase (L-kynurenine hydrolase) |
| HGNC id | 6469 |
|
|
| PROTEIN |
PHYSICAL PROPERTIES
| STRUCTURE
| |
motifs/domains
|
| mono polymer | homomer , dimer |
| HOMOLOGY |
| interspecies | homolog to rattus Kynu |
| Homologene |
| FAMILY | kynureninase family |
| CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION
| intracellular |
| intracellular,cytoplasm |
| basic FUNCTION | pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway |
| CELLULAR PROCESS |
| PHYSIOLOGICAL PROCESS |
| PATHWAY |
| metabolism |
| signaling |
| kynurenine pathway |
| a component |
| INTERACTION |
| DNA |
| RNA |
| small molecule | cofactor, |
| pyridoxal phosphate |
| protein |
| cell & other |
| REGULATION |
| ASSOCIATED DISORDERS |
| corresponding disease(s) | KYNU |
| Susceptibility |
Variant & Polymorphism
|
Candidate gene
| Marker
| Therapy target
|
| |
| ANIMAL & CELL MODELS |