Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol KYNU contributors: - updated : 17-10-2006
HGNC name kynureninase (L-kynurenine hydrolase)
HGNC id 6469
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveliver   highly
 liver   highly
Nervousbrain    
Reproductivefemale systemuteruscervix highly
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandular  
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , dimer
HOMOLOGY
interspecies homolog to rattus Kynu
Homologene
FAMILY kynureninase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
kynurenine pathway
a component
INTERACTION
DNA
RNA
small molecule cofactor,
pyridoxal phosphate
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s) KYNU
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS