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FLASH GENE
Symbol SPRR2D contributors: - updated : 18-03-2006
HGNC name small proline-rich protein 2D
HGNC id 11264
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a central segment built up from nine octapeptide repeats,*K*PEP*
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton
    text cornifin
    basic FUNCTION keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component clustered in the epidermal differentiation complex (EDC)
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by during squamous differentiation of epidermal keratinocytes
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS