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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

ELOVL5

contributors: mct - updated : 16-12-2021

HGNC name	ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
HGNC id	21308

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

SCA38

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function   fusion       fused with MLL in acute myelogemous leukemia tumoral     --over   in mesenchymal-type gastric cancer cells (GCs), leading to ferroptosis sensitization

Susceptibility

Variant & Polymorphism	rs735860 associated with primary open-angle glaucoma (

Candidate gene
Marker	epigenetic biomarker for the risk of type 2 diabetes mellitus
Therapy target

ANIMAL & CELL MODELS

Elovl5 expression was increased in cellular and mouse models of induced obesity-related diabetes