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FLASH GENE
Symbol CHST12 contributors: npt/ - updated : 12-07-2006
HGNC name carbohydrate (chondroitin 4) sulfotransferase 12
HGNC id 17423
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas    
Nervousbrain    
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a C terminal catalytic domain
  • four potential sites for N glycosylation
    • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to murine c4st2-pending
    homolog to Drosophila CG4826
    Homologene
    FAMILY
  • sulfotransferase 2 family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    text type II transmembrane protein
    basic FUNCTION
  • for the synthesis of dermatan and chondroitin sulfate, transfering sulfate to the C-4 position of N-acetylgalactosamine
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS