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FLASH GENE

Symbol

PRDM15

contributors: - updated : 27-02-2007

HGNC name	PR domain containing 15
HGNC id	13999

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	81.00 kb     20 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ZNF298 A - - 6687 - 1178 - Shibuya ZNF298 B - - 6747 - 1198 - Shibuya ZNF298 C - - 6695 - 555 - Shibuya ZNF298 D - - 6575 - 515 - Shibuya

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Lymphoid/Immune lymph node       highly   tonsils       moderately Reproductive female system ovary     moderately

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a SET [Su(var)3-9, Enhancer-of-zeste, Trithorax] domain
	multiple C2H2-type zinc finger (ZnF_C2H2) domains
	several nuclear localization signals (NLSs)
	and PEST sequences

HOMOLOGY

Homologene

FAMILY

PR-domain protein family

CATEGORY

regulatory , transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	ZN2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS