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FLASH GENE

Symbol

PRDM15

contributors: - updated : 27-02-2007

HGNC name	PR domain containing 15
HGNC id	13999

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	21q22.3      Physical location : 43.218.386 - 43.299.591
Genatlas name	positive regulatory domain family protein 15
Synonym name	putative gene containing C2 domain
	zinc finger protein 298
	chromosome 21 open reading frame 83
Synonym symbol(s)	ZNF298, C21orf83, PFM15

DNA

TYPE	functioning gene
STRUCTURE	81.00 kb     20 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ZNF298 A - - 6687 - 1178 - Shibuya ZNF298 B - - 6747 - 1198 - Shibuya ZNF298 C - - 6695 - 555 - Shibuya ZNF298 D - - 6575 - 515 - Shibuya

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Lymphoid/Immune lymph node       highly   tonsils       moderately Reproductive female system ovary     moderately

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a SET [Su(var)3-9, Enhancer-of-zeste, Trithorax] domain
	multiple C2H2-type zinc finger (ZnF_C2H2) domains
	several nuclear localization signals (NLSs)
	and PEST sequences

HOMOLOGY

Homologene

FAMILY

PR-domain protein family

CATEGORY

regulatory , transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	ZN2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS