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FLASH GENE

Symbol

MIS18A

contributors: mct - updated : 03-12-2011

HGNC name	MIS18 kinetochore protein homolog A (S. pombe)
HGNC id	1286

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,nucleoplasm
	intracellular,nucleus,chromatin/chromosome,centromere

basic FUNCTION	essential role for centromere/kinetochore structure and function
	centromeric localization of MIS18 complex is essential for the subsequent recruitment of de novo-synthesized CENPA

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

MIS18A/MIS18BP1/OIP5 complex (MIS18 complex) is accumulated specifically at the telophase-G1 centromere

INTERACTION

DNA

RNA

small molecule

protein

interaction between MAFIP and MIS18A

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS