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FLASH GENE
Symbol PRDM2 contributors: mct - updated : 31-03-2008
HGNC name PR domain containing 2, with ZNF domain
HGNC id 9347
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in acute lymphoblastic leukemia
tumoral       loss of function
by DNA methylation in liver and breast and stomach cancer
tumoral   LOH    
in pheochromocytomas and paragangliomas
tumoral       loss of function
in pheochromocytomas and paragangliomas
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerhemopathy 
therapeutic potential of inhibiting IGF1 pathway in the acute phase of CML (chronic myelogenous leukemia)
ANIMAL & CELL MODELS